首页> 外国专利> INHIBITORS OF BILIC ACID RECYCLING IN THE TREATMENT OF CHOLESTATIC DISEASES OF THE LIVER IN CHILDREN

INHIBITORS OF BILIC ACID RECYCLING IN THE TREATMENT OF CHOLESTATIC DISEASES OF THE LIVER IN CHILDREN

机译:生物酸循环抑制剂在儿童肝脏胆汁淤积性疾病的治疗中的作用

摘要

Children's dosage forms have been proposed for use in the treatment of cholestatic liver diseases in children by non-systemic administration to the patient of a therapeutically effective amount of the infant dosage form containing an inhibitor of an apical sodium-dependent bile acid transporter (ASBTI) or its therapeutically acceptable salt. These children's dosage forms have also been proposed for use in the treatment of liver diseases in children for reducing the bile acid content in serum or liver, treating pruritus, reducing the content of liver enzymes or bilirubin, including non-systemic administration to the patient of a therapeutically effective amount of a child preparation containing ASBTI or its therapeutically acceptable salt.
机译:已经提出了通过非治疗性地向患者非治疗性地给药治疗性量的婴儿剂型的儿童剂型,所述治疗有效量的婴儿剂型包含根尖钠依赖性胆汁酸转运蛋白(ASBTI)的抑制剂。或其治疗上可接受的盐。还建议将这些儿童剂型用于治疗儿童肝脏疾病,以减少血清或肝脏中的胆汁酸含量,治疗瘙痒,减少肝酶或胆红素的含量,包括非全身性给予患者治疗有效量的含有ASBTI或其治疗上可接受的盐的儿童制剂。

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