APPLICATION OF LACHINIMODA IN THE TREATMENT OF PATIENTS WITH CRONE'S DISEASE, WHICH ARE NOT EFFECTIVE THERAPY OF THE FIRST LINE ANTI-TNFα

摘要

This application proposes a method for treating a patient suffering from an anti-TNFα refractory form of Crohn's disease, treating a patient suffering from non-nosocilating form of Crohn's disease, and treating a patient not undergoing surgical treatment for Crohn's disease, the method includes periodically administering the patient to Lachinimode or its pharmaceutically acceptable salt an amount effective to treat the patient. This application proposes a method of induction or maintenance of clinical remission in a patient with Crohn's disease, including intermittent administration of lachinimode to the patient in an amount effective to induce or maintain clinical remission in a patient, the indicated amount of lachinimode is less than 0.5 mg / day.