首页> 外国专利> Pyridin-4-one and fused pyridin-4-one derivatives, process for their preparation, pharmaceutical compositions comprising them and their use in the manufacture of medicaments for the treatment of atherosclerosis

Pyridin-4-one and fused pyridin-4-one derivatives, process for their preparation, pharmaceutical compositions comprising them and their use in the manufacture of medicaments for the treatment of atherosclerosis

机译:吡啶-4-酮和稠合的吡啶-4-酮衍生物,其制备方法,包含它们的药物组合物及其在制备用于治疗动脉粥样硬化的药物中的用途

摘要

Compounds of formula (I): are inhibitors of the enzyme Lp-PLA 2 and are of use in therapy, in particular for treating atherosclerosis.
机译:式(I)的化合物:Lp-PLA 2是Lp-PLA 2酶的抑​​制剂,可用于治疗,特别是用于治疗动脉粥样硬化。

著录项

  • 公开/公告号IL155278A

    专利类型

  • 公开/公告日2015-05-31

    原文格式PDF

  • 申请/专利权人 GLAXO GROUP LIMITED;SMITHKLINE BEECHAM LIMITED;

    申请/专利号IL20030155278

  • 发明设计人

    申请日2003-04-08

  • 分类号A61K;C07D215/20;A61K31/435;A61K31/437;A61K31/4375;A61K31/4545;A61K31/47;A61K31/4709;A61P;A61P3/10;A61P9;A61P9/10;A61P19/02;A61P29;C07D;C07D211/74;C07D215/36;C07D221/04;C07D401/12;C07D471/04;C07D495/04;C07D513/04;

  • 国家 IL

  • 入库时间 2022-08-21 15:15:23

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