Fluorinated derivatives of deferiprone for use as iron chelators in the treatment of neurodegenerative diseases, process for their preparation and pharmaceutical compositions comprising them

摘要

The present invention relates to novel derivatives of deferiprone. In particular, the present invention relates to fluorinated derivatives of deferiprone or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising same, processes for the manufacture thereof and their use in the treatment of neurodegenerative diseases caused by the presence of free iron or iron accumulation in neural tissues and in diseases wherein excess iron must be removed or redistributed.