Conjugates of rgd-containing peptides or rgd-peptidomimetics and porphyrin or (bacterio)chlorophyll photosensitizers and their uses

摘要

Conjugates of porphyrin, chlorophyll and bacteriochlorophyll photosensitizers with RGD-containing peptides or RGD peptidomimetics are provided that are useful for photodynamic therapy (PDT), particularly vascular-targeted PDT (VTP), of tumors and normeoplastic vascular diseases such as age-related macular degeneration, and for diagnosis of tumors by different techniques.