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Formulations for the oral administration of amphotericin b and use thereof in the preparation of medicaments for treating an infectious disease
Formulations for the oral administration of amphotericin b and use thereof in the preparation of medicaments for treating an infectious disease
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机译:两性霉素b的口服给药制剂及其在制备治疗传染病的药物中的用途
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摘要
The present application relates to an oral formulation of amphotericin B and other therapeutic agents, which formulation comprises one or more fatty acid glycerol esters and one or more PEG modified phospholipids or fatty acid esters. The formulation provides enhanced bioavailability and/or increased stability of the therapeutic agent at the low pH found in gastric fluid.
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