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Prognostic and diagnostic methods for ovarian cancer, and compositions and uses thereof for treating same
Prognostic and diagnostic methods for ovarian cancer, and compositions and uses thereof for treating same
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机译:卵巢癌的预后和诊断方法及其组合物和治疗卵巢癌的用途
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摘要
Described herein are gene signatures providing prognostic, diagnostic, treatment and molecular subtype classifications of ovarian cancers through generation of ovarian cancer disease signatures (OCDSs) that account for molecular heterogeneity present in gynecological cancers. An ovarian cancer fixed signature (OCFS) is described which relates to the core programming of disease development, in addition to an ovarian cancer stem cell (OCSC) signature. Development various disease signature, suggests personalized treatment strategies focused on molecular subtypes of gynecological cancers, such as triage tests for patients.
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