Novel process for the preparation of (1s,3ar,6as)-2-(2s)-2({(2s)-2-cyclohexyl-2(pyrazin-2-ylcarbonyl)aminoacety}amino)-3,3-dimethylbutanonyl-n-(3s)-1-cyclopropylamino)-1,2-dioxohexan-3-yl-3,3a,4,5,6,6a-hexahydro-1h-cyclopentacpyrrole-1-carboxamide

摘要

The present invention relates to novel process for the preparation of (lS,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethyl butanoyl]-N-[(3 S)-1 -(cyclopropylamino)-1,2-dioxohexan-3 -yl]-3,3 a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-l-carboxamide compound represented by the structural formula-1. Formula-1