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An immunochromatographic device for implementation of an interferon-gamma release assay for diagnosis of tuberculosis and other infectious diseases
An immunochromatographic device for implementation of an interferon-gamma release assay for diagnosis of tuberculosis and other infectious diseases
The present invention relates to an immunochromatographic device which enables the detection of an infectious disease by testing for the release of interferon gamma from the blood cells of individuals exposed to the microbes responsible for causing the infectious disease. Particularly, the invention provides an immunochromatographic device which detects tuberculosis by testing for the release of interferon gamma from the blood cells of infected individuals. The said device comprises of a sample pad, a detection pad, multiple reagent reservoirs and multiple fluidic paths that can be activated at specified times under user control, as per the requirements of the assay. The device is designed to combine the advantages of high sensitivity and selectivity associated with conventional interferon gamma release assays and the ease of use of devices based on immunochromatography. The device is suitable for point-of-care diagnostics in locations that do not have access to standard clinical laboratory equipment.
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