首页>
外国专利>
CABAZITAXEL PORMULATIONS AND METHODS OF PREPARING THEREOF.
CABAZITAXEL PORMULATIONS AND METHODS OF PREPARING THEREOF.
展开▼
机译:卡巴他赛制剂及其制备方法。
展开▼
页面导航
摘要
著录项
相似文献
摘要
Pharmaceutical formulations comprising cabazitaxel,, solubilizer, tocopherol polyethylene glycol succinate (TPGSF), one or more hydrotropes, optionally one or more agents having a pKa of about 3 to about.6, and optionally one or more antioxidlzing agents, wherein the formulations are substantially free of polysorbat.es and polyethoxylated castor oil, The solubilizer may comprise glycofuroi or ethanol. Pharmaceutical formulations may alternatively comprise, cabazitaxel, solubilizer, optionally one or more agents having a pKa of about 3 to about 6, and optionally one or more antioxidizing agents, wherein, the formulations are substantially free of poiysorbates and polyethoxylated castor oil, 'these formulations may be combined with a diluent, which comprises TPGS and one or more hydrotropes. Methods of administering, the cabazitaxel, formulations include combining the formulations with an infusion solution.
展开▼