Salt related abexinostato novel Crystal form, Preparation method thereof and Pharmaceutical compositions containing it

摘要

Abexinostato tosylate refers to the formula (ii), and the l form of this Crystal is characterized by the Powder diffraction pattern of the same X, the Raman Spectrum of this, and the CP / mas 13C NMR Spectra in Solid State.The Crystal Form I of abexinostato tosylate is intended for Cancer Treatment, more particularly for the treatment of carcinoma, a tumor, Neoplasm, Lymphoma, melanoma, glioma, a sarcoma or blastoma. This Crystalline form is especially valuable in an industrial context in view of its low hygroscopicity