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METHOD OF PURIFYING INFLUENZA VIRUS AND REMOVING MDCK CELL DNA CONTAMINANTS

机译:纯化流感病毒并去除MDCK细胞DNA污染物的方法

摘要

The present invention relates to novel MDCK cells which can be to grow viruses, e.g., influenza viruses, in cell culture to higher titer than previously possible. The MDCK cells can be adapted to serum-free culture medium. The present invention further relates to cell culture compositions comprising the MDCK cells and cultivation methods for growing the MDCK cells. The present invention further relates to methods for producing influenza viruses in cell culture using the MDCK cells of the invention.
机译:本发明涉及新颖的MDCK细胞,其可以在细胞培养物中生长病毒,例如流感病毒,以达到比以前可能更高的滴度。 MDCK细胞可以适应无血清培养基。本发明进一步涉及包含MDCK细胞的细胞培养组合物和用于生长MDCK细胞的培养方法。本发明进一步涉及使用本发明的MDCK细胞在细胞培养物中产生流感病毒的方法。

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