Lacasa high functional redox potential in blood by directed evolution method of production and its applications

摘要

Laccase high functional redox potential in blood by directed evolution method of obtaining and applications. # The present invention discloses a laccase high redox potential obtained by directed molecular evolution that is active in electrophysiological conditions that withstands high concentrations of halides, having significant activity at neutral / alkaline and which is active in human blood plasma and pHs. The present invention relates to the amino acid sequence of said laccase, to the nucleotide sequence encoding said laccase and cells that allow their preparation. The laccase of the invention has applications in various industries: nano-biotechnology, biomedicine, bioremediation, paper industry and fine chemicals.