lipidomic Biomarkers for stable and unstable heart disease

摘要

A stratification test of a subject as a subject vulnerable or not vulnerable to plaque rupture, the test comprising the determination, in a sample of said subject, of the levels of at least two lipid analytes selected from the list consisting of: (i) two or more modified lipid analytes listed in Table 1; (ii) two or more unmodified lipid analytes listed in Table 1; and / or (iii) two or more lipid analytes, in which at least one is a modified lipid analyte listed in Table 1 and at least one is an unmodified lipid analyte listed in Table 1; in which the level of these individual lipid analytes listed in Table 1 is different between vulnerable and non-vulnerable subjects, and in which the level of lipid analytes in the subject with respect to a control identifies the subject as vulnerable or not vulnerable.