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Anti-CD33 antibodies and method for the treatment of acute myeloid leukemia using them

机译:抗CD33抗体和使用其治疗急性髓性白血病的方法

摘要

A specific CD33 antibody, comprising: (i) a heavy chain variable region comprising an amino acid sequence represented by: ** Formula ** and a light chain variable region comprising an amino acid sequence represented by: ** Formula ** (ii) a heavy chain variable region comprising an amino acid sequence represented by: and a light chain variable region comprising an amino acid sequence represented by: ** Formula ** (iii) a chain variable region heavy comprising an amino acid sequence represented by: and a light chain variable region comprising an amino acid sequence represented by: ** Formula ** (iv) a heavy chain variable region comprising an amino acid sequence represented by: * * Formula ** and a light chain variable region comprising an amino acid sequence represented by: ** Formula ** (v) a heavy chain variable region that comprises renders an amino acid sequence represented by: ** Formula **
机译:特异性CD33抗体,其包含:(i)包含由**式**表示的氨基酸序列的重链可变区和包含由**式**表示的氨基酸序列的轻链可变区重链可变区,其包含由以下各项表示的氨基酸序列:和轻链可变区,其包含由以下各项表示的氨基酸序列:**式**(iii)重链可变区,其具有由以下表示的氨基酸序列:和包含由****表示的氨基酸序列的轻链可变区(iv)包含由***表示的氨基酸序列的重链可变区和包含由****表示的氨基酸序列的轻链可变区由:**式**(v)重链可变区,其包含呈递由以下代表的氨基酸序列:**式**

著录项

  • 公开/公告号ES2539627T3

    专利类型

  • 公开/公告日2015-07-02

    原文格式PDF

  • 申请/专利权人 IMMUNOGEN INC.;

    申请/专利号ES20030779105T

  • 申请日2003-11-05

  • 分类号A61K39/395;A61K;A61K39/40;A61K39/42;A61K39/44;C07H21/04;C07K16/28;C07K16/46;C12N5/06;C12N5/16;C12N15;G01N33/574;

  • 国家 ES

  • 入库时间 2022-08-21 15:11:57

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