Solid compositions containing non-steroidal anti-inflammatory drugs, procedures for their preparation and use

摘要

A solid pharmaceutical composition for the production of oral dosage forms, in the form of lozenges, characterized in that it is free of glucose and comprises: - flurbiprofen, or one of its pharmaceutically acceptable salts or one of its esters, in an amount of between 2.5 and 20.0 mg, and pharmaceutically acceptable excipients, according to the following percentages: - flurbiprofen: 0.25-1.0% (w / w) - lubricating agent or agents: glycerol dibehenate, 1.0- 5.0% (w / w) - sweetening agent or agents: potassium acesulfame, 0.5-5.0% (w / w) - diluting agent or agents: mannitol, 84.0-98.0% (w / p) - binding agent or agents: copovidone, 0.25-5.0% (w / w).