Use of ferritin to treat iron deficiency disorders

摘要

H-ferritin receptors on endothelial cells In rat brain rat brain microvasculature are a means for transporting iron across the blood brain barπer. A method for treating an iron deficiency disorder in the brain of a patient comprises administeπng to a patient in need an H- ferritin-iron complex. A method for using H-ferritin as a targeting moiety comprises attaching H-ferritin to a liposome targeted to the brain or cells within the brain. A method for treating an iron overload disorder in a patient comprises administering to a patient a multi subunit ferritin complex at less than 100% iron binding capacity.