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Analysis of antibody drug conjugates by bead-based affinity capture and mass spectrometry
Analysis of antibody drug conjugates by bead-based affinity capture and mass spectrometry
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机译:基于珠的亲和捕获和质谱分析抗体药物偶联物
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摘要
Methods to detect, characterize, and quantitate biological samples after administration of antibody conjugates, antibody-drug conjugates of Formula I, antibodies, and fragments and metabolites thereof, by immunoaffinity bead separation, chromatography, and mass spectrometry are disclosed. Ab-(L-D)
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