GENE EXPRESSION MARKERS FOR PREDICTION OF EFFICACY OF PLATINUM-BASED CHEMOTHERAPY DRUGS

摘要

Methods for predicting the efficacy of a treatment with a platinum-based chemotherapy drug in a patient with cancer are disclosed. The methods generally involve determining an expression level of a gene product that correlates with responsiveness to treatment with a platinum-based chemotherapy drug, which may be oxaliplatin. The cancer may be colorectal cancer.