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Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer

机译:基于表达的前列腺癌不同临床疾病状态识别的系统和方法

摘要

#$%^&*AU2014274499A120150115.pdf#####ABSTRACT A system for expression-based discrimination of distinct clinical disease states in prostate cancer is provided that is based on the identification of sets of gene transcripts, which are characterized in that changes in expression of each gene transcript within a set of gene transcripts can be correlated with recurrent or non-recurrent prostate cancer. The Prostate Cancer Prognostic system provides for sets of "prostate cancer prognostic" target sequences and further provides for combinations of polynucleotide probes and primers derived there from. These combinations of polynucleotide probes can be provided in solution or as an array. The combination of probes and the arrays can be used for diagnosis. The invention further provides further methods of classifying prostate cancer tissue. 6026504_1 (GHMatters) P85779.AU.1 KAROLA
机译:#$%^&* AU2014274499A120150115.pdf #####抽象基于表达的前列腺癌不同临床疾病状态识别系统提供基于鉴定基因转录物集的特征因为在一组基因转录本中每个基因转录本的表达变化可以是与复发性或非复发性前列腺癌相关。前列腺癌的预后系统提供“前列腺癌预后”靶序列的集合,并进一步提供多核苷酸探针和由其衍生的引物的组合。这些组合多核苷酸探针可以溶液或阵列形式提供。探头和该阵列可用于诊断。本发明进一步提供了进一步的方法对前列腺癌组织进行分类。6026504_1(GHMatters)P85779.AU.1 KAROLA

著录项

  • 公开/公告号AU2014274499A1

    专利类型

  • 公开/公告日2015-01-15

    原文格式PDF

  • 申请/专利权人 GENOMEDX BIOSCIENCES INC.;

    申请/专利号AU2014274499A1

  • 发明设计人 DAVICIONI ELAI;

    申请日2014-12-08

  • 分类号C40B40/06;C07H21/00;C12Q1/68;C40B30/04;

  • 国家 AU

  • 入库时间 2022-08-21 15:09:22

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