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A NEUROFILAMENT PEPTIDE FOR USE IN THE TREATMENT OF GLIOMA

机译:用于神经胶质瘤治疗的神经丝肽

摘要

The present invention provides a new drug to treat malignant glioma, which is the most prevalent type of primary tumor of the central nervous system (CNS). The present invention indeed shows that the isolated NFL-TBS 40-63 peptide is highly specific for glioma cells, in which it triggers apoptosis. It is therefore presented here for use in a method for treating malignant glioma. The present invention further relates to the use of the NFL-TBS 40-63 peptide for detecting specifically glioma cells either in vivo, or in vitro.
机译:本发明提供了一种新的治疗恶性神经胶质瘤的药物,所述恶性神经胶质瘤是中枢神经系统(CNS)的最普遍的原发性肿瘤类型。实际上,本发明显示了分离的NFL-TBS 40-63肽对神经胶质瘤细胞具有高度特异性,在其中它触发凋亡。因此,本文提出用于治疗恶性神经胶质瘤的方法。本发明进一步涉及NFL-TBS 40-63肽在体内或体外特异性检测神经胶质瘤细胞中的用途。

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