MICRORNA PROFILES IN HEART FAILURE: METHODS AND SYSTEMS FOR DETECTION AND USE

摘要

The level of miRNAs in a sample from a patient is assayed and used as an indicator of the efficacy of a therapeutic intervention for a cardiovascular disease, such as heart failure. The levels of a plurality of miRNAs, such as myomirs, may be measured. Based on the measured level of the miRNAs, the therapeutic intervention may be modified, adjusted, continued or discontinued. The miRNA level may also be used to assess the severity or disease progression of a cardiovascular disease.