METHOD OF MONITORING AND CONTROLLING A BIOPROCESS USING NEAR- AND MID-INFRARED SPECTROSCOPY

摘要

Methods of monitoring and controlling a bioprocess (100, 200, 300) may include using either a near-infrared or mid-infrared spectroscopic process analytic technology (102, 202, 302) to monitor at least one analyte (104, 204, 304) within the bioprocess, assessing an output (108, 208, 308) of the spectroscopic process analytic technology, and adjusting at least one parameter (110, 210, 310) of the bioprocess in response to the output of the spectroscopic process analytic technology.