PREDICTIVE MRNA BIOMARKERS FOR THE PREDICTION OF THE TREATMENT WITH METHOTREXATE (MTX)

摘要

The present invention relates to predictive mRNA biomarkers which are used in combination with HLA-DRB4 for predicting the treatment with MTX (methotrexate). The present invention further relates to a method for predicting the treatment with MTX (methotrexate), comprising the detection of the predictive mRNA biomarkers in combination with HLA-DRB4 in patient samples, wherein the patients are classified as responders or non-responders.