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REDUCED REPRESENTATION BISULFITE SEQUENCING WITH DIVERSITY ADAPTORS
REDUCED REPRESENTATION BISULFITE SEQUENCING WITH DIVERSITY ADAPTORS
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机译:具有多样性适配器的减少的表示亚硫酸氢盐排队
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摘要
Described herein are methods, compositions and kits for the generation of bisulfite-converted libraries useful for conducting reduced representation bisulfite sequencing (RRBS). The methods described herein can be employed to generate RRBS libraries in a manner that is easier and more cost-efficient than conventional RRBS methods, and can be efficiently sequenced with next generation sequencing (NGS) techniques without the need for genomic, higher diversity sequencing controls such as PhiX spike-ins.
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