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Polypeptide vaccine and vaccination strategy against mycobacterium
Polypeptide vaccine and vaccination strategy against mycobacterium
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机译:多肽疫苗和针对分枝杆菌的疫苗接种策略
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摘要
A vaccine is provided wherein a polypeptide or combination of peptides from M. tuberculosis is administered to a subject to elicit an immune response. The polypeptide vaccine is administered as part of a prime-boost strategy with BCG vaccine to increase the immunoprotection in a subject such that prevention or elimination of disease is achieved. Finally, a pharmaceutical package is provided that encompasses a polypeptide vaccine for M. tuberculosis that when administered to a subject elicits immunoprotection.
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机译:提供了一种疫苗,其中 M I>的多肽或肽的组合。将结核 I>施用于受试者以引发免疫反应。多肽疫苗是与BCG疫苗进行初免-加强免疫策略的一部分,以增加受试者的免疫保护作用,从而实现疾病的预防或消除。最后,提供了一种药物包装,其包含针对I M的多肽疫苗。给予受试者免疫保护。
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