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METHOD FOR PRODUCING IRSOGLADINE MALEATE
METHOD FOR PRODUCING IRSOGLADINE MALEATE
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机译:生产马来酸伊索格拉定的方法
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摘要
Provided is a method for producing high-purity irsogladine maleate with high yield while reducing the production of a by-product. 2,4-diamino-6-(2,5-dichlorophenyl)-1,3,5-triazine is dissolved in an organic solvent while heating and stirring to prepare a solution, then maleic acid is added and dissolved in the solution, and then the resultant solution is cooled to room temperature. In this manner, crystals can be produced with high yield while preventing the coloration of the crystals.
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