首页> 外国专利> compound, pharmaceutical composition, process for preparing a maleate salt, use of a maleate salt, and method for producing a reducing effect on antiangiogenic and / or vascular permeability in a warm-blooded animal

compound, pharmaceutical composition, process for preparing a maleate salt, use of a maleate salt, and method for producing a reducing effect on antiangiogenic and / or vascular permeability in a warm-blooded animal

机译:化合物,药物组合物,马来酸盐的制备方法,马来酸盐的用途以及对温血动物的抗血管生成和/或血管通透性产生降低作用的方法

摘要

"COMPOUND, PHARMACEUTICAL COMPOSITION, PROCESS FOR THE PREPARATION OF A MALEATE SALT, USE OF A MALEATE SALT, AND A METHOD TO PRODUCE A REDUCING EFFECT ON ANTIANGANGENIC AND / OR VASCULAR PERMEABILITY IN A BLOOD ANIMAL". The present invention relates to AZD2171 maleate salt, to particular crystalline forms of AZD2171 maleate salt, to processes for their preparation, to pharmaceutical compositions containing them as an active ingredient, to their use in the manufacture of medicaments for use in producing the reducing effects. of antiangiogenic and / or vascular permeability in warm-blooded animals, such as humans, and their use in a method for treating disease states associated with angiogenesis and / or increased vascular permeability.
机译:“化合物,药物成分,制备马来酸盐的方法,使用马来酸盐以及减少对动物血中抗微生物和/或血管渗透性的作用的方法”。本发明涉及AZD2171马来酸盐,特别是AZD2171马来酸盐的特定结晶形式,涉及它们的制备方法,涉及含有它们作为活性成分的药物组合物,它们在制备用于产生降低作用的药物中的用途。血动物例如人的抗血管生成和/或血管通透性的测定及其在治疗与血管生成和/或血管通透性增加相关的疾病状态的方法中的用途。

著录项

  • 公开/公告号BRPI0417958A

    专利类型

  • 公开/公告日2007-03-27

    原文格式PDF

  • 申请/专利权人 ASTRAZENECA AB;

    申请/专利号BR2004PI17958

  • 发明设计人 JAMES MCCABE;

    申请日2004-12-18

  • 分类号C07D403/12;A61K31/505;A61P35/00;

  • 国家 BR

  • 入库时间 2022-08-21 20:59:26

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