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DEVICE FOR DETERMINING METASTASIS OF CANCER TO SENTINEL LYMPH NODE

机译:测定哨兵淋巴结癌转移的装置

摘要

Provided is a device capable of determining whether or not cancer has metastasized to a sentinel lymph node, such as the axillary lymph node, thickly covered with fat, safely and in a simple manner without confirmation by biopsy or extirpation. Fluorescence generated in a sentinel lymph node upon the excitation of protoporphyrin (a photosensitizing substance) derived from 5-ALA administered to a subject can be detected by passing a hollow tube, into which a small-diameter optical fiber for launching light and the small-diameter optical fiber for receiving light are inserted, through the lymph vessel to identify the presence or absence of the metastasis of cancer cells even before the surgery of cancer or during prognosis.
机译:提供了一种能够以安全且简单的方式确定癌症是否已经转移至前哨淋巴结(例如腋窝淋巴结)的装置,该装置可以安全且简单地进行转移而无需活检或切除的确认。可以通过使空心管穿过中空管来检测在激发受试对象的5-ALA衍生的原卟啉(一种光敏物质)后,在前哨淋巴结中产生的荧光,该中空管中装有用于发射光的小直径光纤和通过淋巴管插入用于接收光的直径直径的光纤,即使在癌症手术之前或在预后过程中也可确定是否存在癌细胞转移。

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