首页> 外国专利> COMPOUNDS HAVING MAGNETIC FUNCTIONALITY, IMPLANTS OR GELS DERIVED FROM SAME, AND USE OF BOTH IN ORDER TO DETERMINE THE ENZYME ACTIVITY OF AN ENZYME

COMPOUNDS HAVING MAGNETIC FUNCTIONALITY, IMPLANTS OR GELS DERIVED FROM SAME, AND USE OF BOTH IN ORDER TO DETERMINE THE ENZYME ACTIVITY OF AN ENZYME

机译:具有磁性功能,由同一衍生物衍生的凝胶或凝胶,以及同时使用两者来确定酶的酶活性的化合物

摘要

The invention relates to an implant or gel including at least one compound having magnetic functionality, which in turn includes a substrate of at least one enzyme involved in regenerating the extracellular matrix and a plurality of magnetic particles. The invention also relates to a compound having magnetic functionality which includes a substrate of at least one enzyme involved in regenerating the extracellular matrix and a plurality of magnetic particles, preferably with no coating or surface modification, or functionalised with carboxyl groups, for the production of an implant or gel for monitoring an enzymatic activity involved in regenerating the extracellular matrix. The substrate is preferably selected from the group that comprises collagen, chondroitin sulphate and hyaluronic acid, and the magnetic particles are superparamagnetic particles.
机译:本发明涉及包含至少一种具有磁性功能的化合物的植入物或凝胶,其进而包括参与再生细胞外基质的至少一种酶的底物和多个磁性颗粒。本发明还涉及具有磁性官能团的化合物,该化合物包括至少一种参与细胞外基质再生的酶的底物和多个磁性颗粒,优选不具有涂层或表面修饰,或被羧基官能化,用于产生β-氨基丁酸酯。用于监测参与细胞外基质再生的酶促活性的植入物或凝胶。基底优选选自胶原,硫酸软骨素和透明质酸,并且磁性颗粒是超顺磁性颗粒。

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