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Magnetic-assisted rapid aptamer selection method for generating high affinity DNA aptamer
Magnetic-assisted rapid aptamer selection method for generating high affinity DNA aptamer
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机译:磁辅助快速适体选择产生高亲和力DNA适体的方法
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摘要
A magnetic-assisted rapid aptamer selection (MARAS) protocol for screening DNA aptamer is proposed. The MARAS protocol is able to efficiently generate aptamers with high affinity and specificity. A rotating magnetic field or alternating magnetic field was used in combination with target-bound magnetic micro-particles or nanoparticles to select DNA aptamers having desirable affinity and specificity to the target.
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