首页> 外国专利> SAMOLLELA COMPRISING SPECTINOMYCINE RESISTENT VECTOR AND METHOD FOR ATTENUATION OF SAMOLLLELA USING THE SAME

SAMOLLELA COMPRISING SPECTINOMYCINE RESISTENT VECTOR AND METHOD FOR ATTENUATION OF SAMOLLLELA USING THE SAME

机译：包含抗分枝杆菌的矢量的小夜蛾和使用该小夜蛾减轻小夜蛾的方法

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摘要

The present invention relates to salmonella comprising a vector expressing a spectinomycin resistant gene and to a method for attenuating salmonella using the same. The salmonella strain according to the present invention is attenuated by being enlarged, having lower motility, and deleting genes related to toxicity due to errors of protein transcription by the spectinomucin. Therefore, the present invention can manufacture live vaccines by simply and economically attenuating the salmonella while minimizing side effects.

机译：沙门氏菌本发明涉及包含表达对壮观霉素抗性基因的载体的沙门氏菌，以及使用该载体减毒沙门氏菌的方法。本发明的沙门氏菌菌株通过扩大，具有较低的运动性而被减毒，并且由于视蛋白粘蛋白的蛋白质转录错误而缺失了与毒性有关的基因。因此，本发明可以通过简单且经济地减毒沙门氏菌同时最小化副作用来制造活疫苗。

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公开/公告号KR20140140265A

专利类型
公开/公告日2014-12-09

原文格式PDF
申请/专利权人 KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION;
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申请/专利号KR20130060851
发明设计人 PARK YONG KEUN;YOON WON SUCK;KIM SIN YEON;
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申请日2013-05-29
分类号C12N1/21;C12N15/63;C12N15/74;A61K39/112;
国家 KR
入库时间 2022-08-21 15:01:28

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