首页> 外国专利> PHARMACEUTICAL, COSMETIC, AND FUNCTIONAL FOOD COMPOSITIONS COMPRISING SMILACIS CHINAE RHIZOMA OF SMILAX CHINA L. FOR ALLERGIC DISEASES

PHARMACEUTICAL, COSMETIC, AND FUNCTIONAL FOOD COMPOSITIONS COMPRISING SMILACIS CHINAE RHIZOMA OF SMILAX CHINA L. FOR ALLERGIC DISEASES

机译:包含中华IL对过敏性疾病的中国根茎类药物,化妆品和功能性食品成分

摘要

The present invention relates to a pharmaceutical composition, a cosmetic composition and a functional food composition including Smilacis chinae rhizoma of Smilax china L. for allergic diseases, and more particularly, to a pharmaceutical composition, a cosmetic composition and a functional food composition including Smilacis chinae rhizome of Smilax china L., that may dissolve in a polar solvent for allergic diseases including an atopic dermatitis of which occurrence increases globally. According to the present invention, the pharmaceutical composition, the cosmetic composition and the functional food composition including the single extract of Smilacis chinae rhizome as an active ingredient are provided. The side effects of, the tolerance to and the toxicity of the compositions are not shown for the long-term administration, and the generation of allergic inflammatory reaction and chronic inflammatory state may be decreased through the decrease of the cytokine concentration of IgE, Th2 and Th1 in blood serum, that play an important role in causing immunological diseases, the restraining of the secretion of histamine of mast cells and an inflammation inducing active material, and the decrease of the permeation and activation of the mast cell of skin tissue. [Reference numerals] (AA) Extract of Smilacis chinae rhizoma (10mg/kg, P.O.); (BB) Smilacis chinae rhizoma (30mg/kg, p.o.)
机译:本发明涉及用于变应性疾病的药物组合物,化妆品组合物和包含Smilax china L.的Smilacis chinae根茎的功能性食品组合物,更具体地,涉及包含Smilacis chinae的药物组合物,化妆品组合物和功能性食品组合物Smilax china L.的根状茎,可能溶于极性溶剂,用于过敏性疾病,包括特应性皮炎,在全球范围内发病率不断增加。根据本发明,提供了包含S草根茎的单一提取物作为活性成分的药物组合物,化妆品组合物和功能性食品组合物。长期给药未显示出该组合物的副作用,耐受性和毒性,并且通过降低IgE,Th2和Th2的细胞因子浓度可以减少过敏性炎症反应和慢性炎症状态的产生。血清中的Th1在引起免疫疾病,抑制肥大细胞组胺的分泌和诱导炎症的活性物质以及减少皮肤组织肥大细胞的渗透和激活中起重要作用。 [附图标记](AA)mil草提取物(10mg / kg,P.O。); (BB)mil草根茎(30mg / kg,p.o.)

著录项

  • 公开/公告号KR101458763B1

    专利类型

  • 公开/公告日2014-11-12

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20140000695

  • 发明设计人 신화섭;김순도;김효정;

    申请日2014-01-03

  • 分类号A61K36/90;A61K36/896;A61K8/97;A61P27/14;

  • 国家 KR

  • 入库时间 2022-08-21 15:01:21

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