Screening method using MG53-UBE2H interaction for the treatment of type 2 diabetes

摘要

invention UBE2H (ubiquitin-conjugating enzyme E2H) and MG53 (mitsugumin 53) by determining the drug inhibiting the interaction with type 2 diabetes , the present invention relates to a method for screening a therapeutic agent for type 2 diabetes . Drugs that inhibit the interaction of the MG53 and UBE2H increases the amount of IRS-1 to treat type 2 diabetes by increasing insulin sensitivity . ;