首页> 外国专利> METHOD FOR MANUFACTURING POROUS THREE-DIMENSIONAL NANOFIBROUS SCAFFOLD, AND POROUS THREE-DIMENSIONAL NANOFIBROUS SCAFFOLD MANUFACTURED BY THE METHOD

METHOD FOR MANUFACTURING POROUS THREE-DIMENSIONAL NANOFIBROUS SCAFFOLD, AND POROUS THREE-DIMENSIONAL NANOFIBROUS SCAFFOLD MANUFACTURED BY THE METHOD

机译:制造多孔三维纳米纤维脚手架的方法,以及用该方法制造的多孔三维纳米纤维脚手架

摘要

The present invention relates to a method for manufacturing a porous three-dimensional nanofibrous scaffold and a porous three-dimensional nanofibrous scaffold manufactured thereby. According to the method for manufacturing a porous three-dimensional nanofibrous scaffold of the present invention, a manufactured scaffold can have a three-dimensional structure formed stably by conducting electrospinning while adjusting the weight percentage of polymers. Also, the porosity, height and thickness of the manufactured scaffold can be adjusted easily by using a solvent with surface tension and density lower than those of water and adjusting flow rate thereof during electrospinning. Moreover, a scaffold having large pores distributed uniformly thereon can be manufactured by forming the pores using a laser process, specifically a femtosecond laser process. Therefore, an optimal environment for growing cells to be proliferated inside or outside a body is provided as a surface area is increased to increase the adherence range of the cells and enable the cells to penetrate into the scaffold.
机译:本发明涉及一种制造多孔三维纳米纤维支架的方法和由此制造的多孔三维纳米纤维支架。根据本发明的多孔三维纳米纤维支架的制造方法,所制造的支架可以具有通过在调节聚合物的重量百分比的同时进行电纺丝而稳定地形成的三维结构。另外,通过使用表面张力和密度低于水的溶剂并在静电纺丝过程中调节其流速,可以容易地调节所制造的支架的孔隙率,高度和厚度。此外,可以通过使用激光工艺,特别是飞秒激光工艺形成孔来制造具有均匀分布在其上的大孔的支架。因此,随着表面积增加以增加细胞的粘附范围并使细胞能够渗透到支架中,提供了用于使细胞在体内或体外增殖的最佳环境。

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