-Glucosidase inhibiting compounds isolated from Vigna nakashimae, pharmaceutical composition for treatment or prevention of -Glucosidase related diseases comprising the same, and food composition for improvement of -Glucosidase related diseases comprising the same

摘要

The present invention of the formula 1 to a compound represented by the alpha 3 containing one or more compounds as an effective component relates to food compositions containing glucosyl when A pharmaceutical composition for preventing or treating a disease associated Days, this. The invention also relates to novel compounds represented by the general formula (1) in a bit separation dolpat. In addition, the present invention is to obtain a bit by bit dolpat extract extracted dolpat as a lower alcohol or a solvent selected from a mixture thereof in water, C1 ~ C4; Obtaining the extract dolpat little ethanol, chloroform, methanol, or in a little water to fractionate the solution one or more selected from the group consisting dolpat ethanol, chloroform, methanol, or water fraction; And a compound of formula 1 to show a 3, comprising the step of obtaining at least one compound selected from the group consisting of the fractions to the column to perform chromatography of the formula 1 to 3 or any one of compounds represented by compound It relates to a process for preparing a compound of at least one selected from the group consisting of. Formula 1 to one or more compounds of compounds represented by 3 of the present invention are alpha-glucosidase and is excellent activity to inhibit during Days, alpha-glucosidase enzyme and slowly during Days binding (binding) It serves to gradually strongly inhibited the enzyme activity, alpha-it may be useful as a preventive or therapeutic composition during Days glucosidase-related diseases. ;