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Detection Method of Sensitive Genes for Low-Dose-Rate Radiation and Genes Detected by This Method

机译:低剂量率辐射敏感基因的检测方法及以此方法检测的基因

摘要

The present invention relates to a method for detecting the gene sensitive to ionizing radiation , and low-level gene detected by the above method and, more particularly, to a low level of ionizing radiation irradiation in cancer induced AKR / J mice with normal ICR mice , and wherein the collected thymus , performed for the microarray on the thymus and classifies the immune and apoptotic gene , the the excavation and amplifying the gene in the cancer by measuring the expression level of the object and provide a sensitive method for detecting the gene involved in the low-level ionizing radiation thymus tumor suppressor is verified in normal individuals . The present invention in this configuration is effective to prevent the intervention of the disturbance variable to accurately detect the gene -specific reaction to the radiation . ;
机译:本发明涉及一种检测对电离辐射敏感的基因的方法,以及通过上述方法检测的低水平基因,更具体地,涉及一种在具有正常ICR小鼠的癌症诱导的AKR / J小鼠中低水平的电离辐射辐射的方法。并在胸腺上进行微阵列的收集的胸腺,对免疫和凋亡基因进行分类,通过测量物体的表达水平来挖掘和扩增癌症中的基因,并提供了一种灵敏的方法检测相关基因低水平电离辐射胸腺肿瘤抑制剂在正常个体中得到证实。在这种配置中的本发明有效地防止干扰变量的干预以准确地检测对辐射的基因特异性反应。 ;

著录项

  • 公开/公告号KR101472789B1

    专利类型

  • 公开/公告日2014-12-15

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20120049560

  • 申请日2012-05-10

  • 分类号C12Q1/68;C12N15/11;

  • 国家 KR

  • 入库时间 2022-08-21 15:01:05

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