首页> 外国专利> A COMPOSITION FOR IMPROVING MEMORY AND PREVENTING OR TREATING COGNITIVE DYSFUNCTION COMPRISING EPIGALLOCATECHIN-3-GALLATE AND LUTEOLIN

A COMPOSITION FOR IMPROVING MEMORY AND PREVENTING OR TREATING COGNITIVE DYSFUNCTION COMPRISING EPIGALLOCATECHIN-3-GALLATE AND LUTEOLIN

机译:包含EPIGALLOCATECHIN-3-GALLATE和LUTEOLIN的改善记忆力和预防或治疗认知功能障碍的组合物

摘要

The present invention relates to a composition for promoting memory and preventing or treating diseases related to cognitive dysfunction including epigallocatechin-3-gallate and luteolin as active ingredients. More specifically, the mixture of epigallocatechin-3-gallate and luteolin of the present invention exhibits enhancement of memory in Morris water-maze test and passive avoidance test using a mouse in which memory loss is induced by beta-amyloid (A beta_1-42) which is one of factors causing dementia, thereby being used as pharmaceutical compositions and health food for preventing and treating diseases related to cognitive dysfunction and memory.
机译:本发明涉及用于促进记忆和预防或治疗与认知功能障碍有关的疾病的组合物,包括表没食子儿茶素-3-没食子酸酯和木犀草素作为有效成分。更具体地,本发明的表没食子儿茶素-3-没食子酸酯和木犀草素的混合物在莫里斯水迷宫试验和使用由β-淀粉样蛋白(A beta_1-42)引起的记忆丧失的小鼠的被动回避试验中表现出记忆增强。它是引起痴呆的因素之一,因此被用作预防和治疗与认知功能障碍和记忆有关的疾病的药物组合物和保健食品。

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