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METHOD OF PROTECTING ACTIVE INGREDIENT FROM DEGRADATION DURING PELLETING

机译:制粒过程中降解过程中活性成分的保护方法

摘要

Systems for protection against degradation during pelletization of one or more physiological or pharmacologically active substances include, in particular, microparticle or granular compositions for use in the livestock sector and / or the veterinary sector. The microparticles comprise a core comprising one or more substances having pharmacological action, a food supplement or diagnostic medium, said one or more substances being characterized by the presence of a basic functional group comprising an amine functional group in a chemical structure . The core also comprises one or more carboxylic acids and / or salts thereof, and ultimately one or more excipients. The core is coated by an outer layer of fat or wax, and preferably by a mixture of glycerides of fatty acids.
机译:用于在一种或多种生理或药理活性物质造粒过程中防止降解的系统尤其包括用于畜牧业和/或兽医业的微粒或颗粒组合物。微粒包括包含一种或多种具有药理作用的物质,食物补充剂或诊断介质的核,所述一种或多种物质的特征在于在化学结构中存在包含胺官能团的碱性官能团。核心还包含一种或多种羧酸和/或其盐,以及最终一种或多种赋形剂。核心被脂肪或蜡的外层覆盖,优选被脂肪酸甘油酯的混合物覆盖。

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