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A METHOD OF PREPARING A HIGHLY PURE POTASSIUM SALT OF AZILSARTAN MEDOXOMIL

机译:一种制备阿扎拉坦美托莫尔的高纯钾盐的方法

摘要

The present invention also relates to a process for the preparation of a compound of formula (I) wherein a solvate of an azurturate of a compound of formula (II), a solvent selected from the group consisting of dimethylacetamide or N-methylpyrrolidone or other solvents and mixtures thereof, (I), which is recrystallized from N-methylpyrrolidine or other solvents and mixtures thereof, and which in the next step is converted to the potassium salt using a potassium source in a suitable solvent, And a method for manufacturing the same. (I) (II)
机译:本发明还涉及制备式(I)化合物的方法,其中式(II)化合物的天青酸酯的溶剂化物,选自二甲基乙酰胺或N-甲基吡咯烷酮的溶剂或其他溶剂。及其混合物,(I),其在N-甲基吡咯烷或其他溶剂中重结晶,以及在下一步中使用钾源在合适的溶剂中转化为钾盐,及其制造方法。 (一)(二)

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