首页> 外国专利> APTAMER HAVING SPECIFIC BINDING ABILITY FOR VASPIN AND BIOSENSOR USING THEROF

APTAMER HAVING SPECIFIC BINDING ABILITY FOR VASPIN AND BIOSENSOR USING THEROF

机译:具有使用THEROF的VASPIN和生物传感器具有特定绑定能力的Aptamer

摘要

The present invention relates to an aptamer capable of specifically binding to vaspin and a biosensor using the same and, more specifically, to an aptamer capable of specifically binding to vaspin and a sandwich-type biosensing method using a dual DNA aptamer. According to the present invention, by using the DNA aptamer capable of specifically binding to vaspin, it is possible to more sensitively detect concentration of the vaspin in blood. A transition in the concentration of vaspin in blood is associated with obesity and a blood glucose metabolism, thereby being able to be used for diagnosing a type 2 diabetes by measuring the concentration of vaspin in blood.
机译:本发明涉及能够与vaspin特异性结合的适体和使用该适体的生物传感器,更具体地,涉及一种能够与vaspin特异性结合的适体和使用双DNA适体的夹心型生物传感方法。根据本发明,通过使用能够与vaspin特异性结合的DNA适体,可以更灵敏地检测血液中vaspin的浓度。血液中vaspin浓度的变化与肥胖症和血糖代谢有关,因此能够通过测量血液中vaspin的浓度用于诊断2型糖尿病。

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