Peptides derived from microalgae Navicula incerta protein hydrolysate for inhibiting liver fibrosis, and health food containing the same

摘要

the invention inhibit liver fibrosis butterfly Temecula royalties for microalgae reuta (Navicula Incerta) of papain hydrolyzate It relates to peptides, to dietary supplements containing it derived. In the present invention, we studied the effect of the peptides on alcohol-induced liver toxicity, and hepatic fibrosis in the liver cells, two named HepG2 / CYP2E1 and LX-2 cells (HSC). In accordance with the present invention, the above two peptides was highly active against both alcoholic liver injury. According to the present invention, NIPP-1, and mechanism of action of NIPP-2 for the liver damage it is present. According to the experimental data of the present invention, it was in all cases NIPP-1 had a higher activity than the NIPP-2, both of the peptides can be used as an effective component of food additives, functional food material and the pharmacological agent. ;