ANISOTROPIC POLYPEPTIDE NANOSTRUCTURES WITH ENVIROMENTALLY RESPONSIVENESS BY SPONTANEOUS STRUCTURE TRANSFORMATION AND METHOD FOR PREPARING THEREOF

摘要

The present invention is an anisotropic protein nanostructure and a method of manufacturing the structure according to the voluntary conversion relates to, and more specifically with a chemical cross-linking reactive stimulation (Chemical crosslinking) a homopolymer containing a free block and the (Monoblock polymer) chemical cross-linking with a protein or as a block, and chemical stimulation reactive non-crosslinked binding (Chemical uncrosslinking) double copolymer comprising a free block (Diblock copolymer) elastin polypeptide (Elastin-like polypeptide, using the spontaneous conversion structure from ELP) maintaining the physicochemical and partitioned with anisotropic structure having a magnetic pole reactive protein nanoparticles at the same time Method for producing, and the use by the anisotropic nanostructures protein produced by the method, the anisotropic structure on the aqueous protein nanostructures spontaneously transformed anisotropic nanoparticles protein structure and the anisotropic nanostructures. The anisotropic nanostructure protein of the present invention may be used to keep the segmented physical and chemical reactivity, and therefore useful in the stimulation of the drug delivery system, bio-imaging, biosensing and biomedical nanodevices simultaneously. ;