首页> 外国专利> Compositions for prevention, improvement and treatment of Aging Phenotypes Comprising Recombinant Fusion Protein with Vibrio vulnificus Flagellin and Pathogenic Antigen

Compositions for prevention, improvement and treatment of Aging Phenotypes Comprising Recombinant Fusion Protein with Vibrio vulnificus Flagellin and Pathogenic Antigen

机译：预防，改善和治疗包含重组融合蛋白与创伤弧菌鞭毛蛋白和致病性抗原的衰老表型的组合物

页面导航

摘要
著录项
相似文献

摘要

The present invention septic vibrio bacteria ( Vibrio vulnificus ) containing the recombinant proteins fused to the protein antigen and the flagellar components of Plastic jelrin aging preventing agents as an effective ingredient , and a composition for the improvement or treatment . According to the present invention it caused depending on the extrinsic aging using recombinant proteins of the present invention, improving the functionality and advantages for enhancing immunity. In addition, the composition of the present invention may be an immune easily through the mucosa . ;

机译：本发明的败血性弧菌（ Viulio vulnificus ）含有与蛋白抗原和塑料水母防止老化的鞭毛成分融合的重组蛋白作为有效成分，以及用于改善或治疗的组合物。根据本发明，其依赖于使用本发明的重组蛋白的外部老化引起，从而提高了功能性和增强免疫力的优势。另外，本发明的组合物可以容易地通过粘膜免疫。 ; 展开▼

著录项

公开/公告号KR1015203360000B1

专利类型

公开/公告日2015-05-14

原文格式PDF

申请/专利权人
展开▼

申请/专利号KR1020120138234

发明设计人 조경아;이준행;임재성;
展开▼

申请日2012-11-30

分类号A61K38/17;A61K38/16;A61P1/00;A61P19/00;

国家 KR

入库时间 2022-08-21 14:58:12

相似文献

专利

外文文献

中文文献

1. 包含粘土矿物复合物的用于预防、改善及治疗炎症性结肠炎的组合物、组合物的制备方法及改善及治疗炎症性结肠炎的方法 [P] . 中国专利： CN113710279A . 2021-11-26

2. 包含从鞭毛蛋白衍生的TLR5激动剂作为有效成分的用于预防或治疗移植物抗宿主病的组合物 [P] . 中国专利： CN113993538A . 2022-01-28

3. Compositions for prevention improvement and treatment of Aging Phenotypes Comprising Recombinant Fusion Protein with Vibrio vulnificus Flagellin and Pathogenic Antigen [P] . 韩国专利： KR101749318B1 . 2017-06-22

机译：预防和治疗包含重组融合蛋白与创伤弧菌鞭毛蛋白和致病性抗原的衰老表型的组合物

4. Compositions for prevention improvement and treatment of Aging Phenotypes Comprising Recombinant Fusion Protein with Vibrio vulnificus Flagellin and Pathogenic Antigen [P] . 韩国专利： KR101749317B1 . 2017-06-22

机译：预防和治疗包含重组融合蛋白与创伤弧菌鞭毛蛋白和致病性抗原的衰老表型的组合物

5. Compositions for prevention, improvement and treatment of Aging Phenotypes Comprising Recombinant Fusion Protein with Vibrio vulnificus Flagellin and Pathogenic Antigen [P] . 韩国专利： KR20150045418A . 2015-04-28

机译：预防，改善和治疗包含重组融合蛋白与创伤弧菌鞭毛蛋白和致病性抗原的衰老表型的组合物

1. THE ROLE OF RECOMBINANT HUMAN FUSION PROTEIN IL-6／IL-2 （CH925） IN HEPADNA VIRUS INFECTION TREATMENT [J] . 米志宝, 赵春华, 张习坦, 中国医学科学杂志：英文版 . 1995,第004期

2. Enhancement of antigen-specific humoral immune responses and protein solubility through conjugation of bacterial flagellin, Vibrio vulnificus FlaB, to the N-terminus of porcine epidemic diarrhea virus surface protein antigen S0 [J] . Oh Seo-ho, Cho Young-Saeng Kim, Lee Ho-Bin, Journal of Veterinary Science . 2019,第6期

3. Enhancement of antigen-specific humoral immune responses and protein solubility through conjugation of bacterial flagellin, Vibrio vulnificus FlaB, to the N-terminus of porcine epidemic diarrhea virus surface protein antigen S0 [J] . Seo-ho Oh, Young-Saeng Kim Cho, Ho-Bin Lee, Journal of Veterinary Science . 2019,第6期

4. Phase 1 Safety and Immunogenicity Study of a Quadrivalent Seasonal Flu Vaccine Comprising Recombinant Hemagglutinin-Flagellin Fusion Proteins [J] . C. Jo White, Casey Johnson, Cynthia Strout, Open Forum Infectious Diseases . 2016,第1期

5. The antigenicity of the flagellin, outer membrane proteins and lipopolysaccharide of Vibrio harveyi [C] . Ying-xue Qin, Qing-pi Yan 2010 International Conference on Bioinformatics and Biomedical Technology (ICBBT 2010) . 2010

6. Anti-transferrin receptor IgG3 -avidin fusion proteins as universal drug delivery systems and direct tumoricidal agents for the treatment of hematopoietic malignancies. [D] . Ng, Patrick Ping Hong. 2005

7. Enhancement of antigen-specific humoral immune responses and protein solubility through conjugation of bacterial flagellin Vibrio vulnificus FlaB to the N-terminus of porcine epidemic diarrhea virus surface protein antigen S0 [O] . Seo-ho Oh, Young-Saeng Kim Cho, Ho-Bin Lee, 2019

8. Enhancement of antigen-specific humoral immune responses and protein solubility through conjugation of bacterial flagellin, Vibrio vulnificus FlaB, to the N-terminus of porcine epidemic diarrhea virus surface protein antigen S0 [O] . Seo-ho Oh, Young-Saeng Kim Cho, Ho-Bin Lee, 2019

1. 人参、银杏叶提取物对自然衰老认知障碍大鼠认知功能的改善作用及相关机制研究 [C] . 丛伟红 ,刘建勋 ,徐立 . 第四届中国衰老与抗衰老学术大会 . 2013

2. 创伤弧菌对慢性酒精性肝病大鼠的致病性及药物治疗的研究 [A] . 赵初环 . 2006