首页> 外国专利> EXPRESSION CONSTRUCT FOR INTERLEUKIN-2 USING HUMAN SERUM ALBUMIN

EXPRESSION CONSTRUCT FOR INTERLEUKIN-2 USING HUMAN SERUM ALBUMIN

机译:人血清白蛋白表达白介素2的表达构建

摘要

The present invention relates to an expression construct for interleukin-2 for a yeast, and a yeast containing the same, wherein the expression construct for interleukin-2 for a yeast comprises: a methanol oxidase promoter; a human serum albumin or a fragment gene thereof; and an interleukin-2 gene. The expression construct for interleukin-2 for a yeast according to the present invention allows to obtain a fusion protein by secretory expression involving a human serum albumin (HSA) with low costs, and allows to easily separate a recombinant interleukin-2 therefrom, thereby being useful for mass production of a recombinant interleukin-2 protein with high purity.
机译:本发明涉及用于酵母的白介素-2的表达构建体,以及含有该表达构建体的酵母,其中用于酵母的白介素-2的表达构建体包括:甲醇氧化酶启动子;和人血清白蛋白或其片段基因;和白介素2基因。根据本发明的用于酵母的白介素-2的表达构建体允许通过涉及人血清白蛋白(HSA)的分泌表达以低成本获得融合蛋白,并允许容易地从其分离重组白介素-2,从而成为可用于大量生产高纯度的重组白介素2蛋白。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号