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Recombinant Protein Comprising Epitope of Fowl Adenovirus fiber 2 Protein and Antibody thereto

机译:包含禽腺病毒纤维2蛋白表位的重组蛋白及其抗体

摘要

The present invention relates to a recombinant protein comprising the antigenic determinant of the poultry adenovirus fiber 2 protein and an antibody thereto. More specifically, a recombinant protein comprising an antigenic determinant of the poultice adenovirus Fib 2 protein, a gene encoding the recombinant protein, an expression vector containing the gene, a host cell transformed with the expression vector, a preparation of the recombinant protein A vaccine composition for the treatment or prevention of poultry adenovirus infection comprising the recombinant protein as an active ingredient, an antibody recognizing the recombinant protein to be effective And a method for treating or preventing poultry adenovirus infection by administering the vaccine composition or the pharmaceutical composition to an animal other than a human. The present invention also relates to a method for treating or preventing poultry adenovirus infection, Will. The recombinant poultry adenovirus fiber 2 protein and the antibody thereof according to the present invention can be effectively used for treating or preventing infectious diseases against poultry adenovirus more efficiently.
机译:本发明涉及包含家禽腺病毒纤维2蛋白的抗原决定簇和其抗体的重组蛋白。更具体地,一种重组蛋白,其包含家禽腺病毒Fib 2蛋白的抗原决定簇,编码该重组蛋白的基因,包含该基因的表达载体,用该表达载体转化的宿主细胞,该重组蛋白A疫苗组合物的制备。用于治疗或预防以重组蛋白为有效成分的家禽腺病毒感染的方法,识别该重组蛋白有效的抗体以及通过将疫苗组合物或药物组合物施用于动物体内来治疗或预防家禽腺病毒感染的方法比人类本发明还涉及治疗或预防家禽腺病毒感染的方法。根据本发明的重组家禽腺病毒纤维2蛋白及其抗体可以有效地更有效地用于治疗或预防针对家禽腺病毒的传染病。

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