首页> 外国专利> Pharmaceutical formulation containing liposome nanoparticles that encapsulate poorly water soluble drug having good long stability and preparation method thereof

Pharmaceutical formulation containing liposome nanoparticles that encapsulate poorly water soluble drug having good long stability and preparation method thereof

机译:包封水溶性差,药物稳定性好的脂质体纳米颗粒的药物制剂及其制备方法

摘要

The present invention relates to a pharmaceutical composition having excellent long-term stability including liposome nanoparticles encapsulating an insoluble drug and a method for producing the same, wherein the size of the liposome nanoparticles encapsulating the poorly soluble drug according to the present invention is 30 -900 nm, the solubility of the pharmaceutical preparation containing the same is improved and the long-term stability is improved, so that the bioavailability of the drug can be improved. In addition, since the pharmaceutical preparation can be manufactured by an easy manufacturing method, it can be usefully applied to a poorly soluble drug that requires stability.
机译:本发明涉及具有优异的长期稳定性的药物组合物,其包括包封不溶性药物的脂质体纳米颗粒及其制备方法,其中根据本发明的包封难溶性药物的脂质体纳米颗粒的尺寸为30 -900可以提高包含该纳米颗粒的药物制剂的溶解度,并且改善其长期稳定性,从而可以提高药物的生物利用度。另外,由于可以通过容易的制造方法制造药物制剂,因此可以有效地用于需要稳定性的难溶性药物。

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