首页> 外国专利> Mutant Strain with improved Amino acid production by inactivating malic enzyme or lactate dehydrogenase

Mutant Strain with improved Amino acid production by inactivating malic enzyme or lactate dehydrogenase

机译:通过灭活苹果酸酶或乳酸脱氢酶提高氨基酸产量的突变株

摘要

The present invention relates to a mutant strain of arginine or glutamine production including a malic enzyme or a lactate dehydrogenase, and a method for producing the same. According to the present invention, by inactivating a malic acid enzyme or a lactate dehydrogenase, it is possible to provide a mutant having an improved arginine or glutamine production ability and yield per unit without lowering the growth of an arginine or glutamine producing ability strain including a wild type or an activated malic acid enzyme or a lactate dehydrogenase A strain can be produced to produce arginine or glutamine. In addition, since the mutant strains of the present invention can be used to improve the yield and yield per unit of arginine or glutamine, there is an advantage in cost reduction when arginine or glutamine is used as a raw material.
机译:本发明涉及包括苹果酸酶或乳酸脱氢酶的精氨酸或谷氨酰胺生产的突变菌株及其生产方法。根据本发明,通过使苹果酸酶或乳酸脱氢酶失活,可以提供具有提高的精氨酸或谷氨酰胺生产能力和单位产量的突变体,而不会降低包括可以产生野生型或活化的苹果酸酶或乳酸脱氢酶A菌株以产生精氨酸或谷氨酰胺。另外,由于本发明的突变菌株可以用于提高精氨酸或谷氨酰胺的产率和每单位的产率,所以当使用精氨酸或谷氨酰胺作为原料时,在降低成本方面具有优势。

著录项

  • 公开/公告号KR101565024B1

    专利类型

  • 公开/公告日2015-11-03

    原文格式PDF

  • 申请/专利权人 대상 주식회사;

    申请/专利号KR20130164519

  • 申请日2013-12-26

  • 分类号C12N1/21;C12N15/52;C12P13/10;C12P13/14;

  • 国家 KR

  • 入库时间 2022-08-21 14:57:30

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