首页> 外国专利> Process for the preparation of regenerated rudiments of hair follicles for transplantation, where the supervisory HAIR COLOR, COMPOSITION CONTAINING rudiment of regenerated hair follicles for transplantation and grafting method to regenerate the rudiments of hair follicles

Process for the preparation of regenerated rudiments of hair follicles for transplantation, where the supervisory HAIR COLOR, COMPOSITION CONTAINING rudiment of regenerated hair follicles for transplantation and grafting method to regenerate the rudiments of hair follicles

机译:制备用于移植的毛囊的再生残基的方法,其中监督头发颜色,包含用于移植的再生毛囊的残基的组成和嫁接方法以再生毛囊的残基

摘要

1. A method of obtaining a regenerated germ of a hair follicle for transplantation, in which the color of the hair growing after transplantation is controlled, including: obtaining a first cell mass containing mesenchymal cells, obtaining a second cell mass containing epithelial cells, obtaining a cell mass containing pigment stem cells , the connection of the cell mass containing pigment stem cells with at least one of the first cell mass and the second cell mass, and then close clocking the first cell mass and the second cell, at least one of which is connected to the cell mass containing pigment stem cells, and culturing them in a substrate. 2. The method according to claim 1, whereby the first cell mass mainly consists of mesenchymal cells. The method according to claim 1, wherein the second cell mass mainly consists of epithelial cells. The method of claim 1, wherein the cell mass containing pigment stem cells undergoes a unifying treatment. The method according to any one of paragraphs. 1-4, according to which pigmented stem cells are melanoblasts originating from the region under the protrusion, or melanocyte precursor cells originating from the base of the hair matrix. 6. The method according to any one of paragraphs. 1-4, according to which pigmented stem cells are melanocyte precursor cells originating from the base of the hair matrix. 7. The method according to any one of paragraphs. 1-4, according to which, when connecting the cell masses together, the ratio of the number of cells in the first cell mass or
机译:1。一种获得用于移植的毛囊的再生胚的方法,其中,控制移植后生长的头发的颜色,包括:获得包含间充质细胞的第一细胞团,获得包含上皮细胞的第二细胞团,获得含有色素干细胞的细胞团,含有色素干细胞的细胞团与第一细胞团和第二细胞团中的至少一个的连接,然后将第一细胞团和第二细胞团,至少一个将其连接至包含色素干细胞的细胞团,并在底物中培养它们。 2.根据权利要求1所述的方法,其中所述第一细胞团主要由间充质细胞组成。 2.根据权利要求1所述的方法,其中,所述第二细胞块主要由上皮细胞组成。 2.根据权利要求1所述的方法,其中,所述含有色素干细胞的细胞团经过统一处理。根据段落中任一项的方法。参照图1-4,其中有色干细胞是源自突起下方区域的黑素母细胞,或源自头发基质的黑素细胞前体细胞。 6.根据段落中任一项的方法。参照图1-4,其中有色干细胞是源自毛发基质底部的黑素细胞前体细胞。 7.根据段落中任一项的方法。参照图1-4,其中,当将单元块连接在一起时,第一单元块中的单元数目的比率为

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