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METHOD (VARIANTS) AND KIT FOR DIAGNOSIS OF INFECTION URINARY TRACT, method of treatment and detection of predisposition to infection urinary tract
METHOD (VARIANTS) AND KIT FOR DIAGNOSIS OF INFECTION URINARY TRACT, method of treatment and detection of predisposition to infection urinary tract
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机译:诊断感染性尿道的方法(试剂盒),治疗方法和感染尿路易感性的检测
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摘要
1. A method of detecting urinary tract infection in a patient, comprising: a) providing a sample from the patient; and b) detecting in said sample BCL6.2 CD1d receptor and biomarker expression. A method according to Claim. 1, comprising detecting the presence of mRNA for the receptor and CD1d BCL6.3. The method of claim. 2, comprising reacting said mRNA for the receptor and CD1d BCL6 a nucleic acid probe complementary to said mRNA for the receptor and CD1d BCL6.4. A method according to Claim. 1, comprising detecting the presence of receptor polypeptides and CD1d BCL6.5. A method according to claim. 4, comprising reacting said CD1d receptor and BCL6 polypeptides with an antibody specific to said polypeptide and BCL6 CD1d receptor and detecting the binding of said antibody to said polypeptide receptor and CD1d BCL6.6. A method according to Claim. 1, in which the test is chelovek.7. The method of claim. 1, wherein the sample comprises urine, blood, and / or cell or tissue puzyrya.8 bladder. A method for treating urinary tract infections, comprising: a) providing a sample of the test; b) detecting expression of CD1d receptor and BCL6 in said sample; c) on the basis of said expression BCL6 CD1d receptor and suppression of inflammation with monoclonal antibodies and / or soluble receptors and / or anti-protease inhibitors, respectively, or a polypeptide BCL6.9 receptor and CD1d gene. Set to describe infections of the urinary tract in a test comprising: a) a reagent possessing the ability to specifically detect the presence or absence of expression of BCL6 and CD1d receptor; and b) instructions for using said kit to describe infections of the urinary tract in that ispytuemom.10. The kit of claim. 9, in which the decree
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